Detection and management of lipid disorders in diabetes. American Diabetes Association.

A ltered concentrations of blood plasma lipoproteins are powerful predictors of coronary heart disease (CHD) and of other manifestations of atherosclerosis. Reduction of elevated lowdensity lipoprotein cholesterol (LDL cholesteroD and concomitant increases in highdensity lipoprotein cholesterol (HDL cholesterol) have been shown to reduce myocardial infarction and death from CHD in people with no previous history of vascular events. Other studies using angiography have demonstrated that the atherosclerotic lesions can be stabilized or caused to regress in the coronary vessels of patients who have clinically evident disease.